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Enzymatic synthesis of structure-free DNA with pseudo-complementary properties

Long single-stranded DNAs and RNAs possess considerable secondary structure under conditions that support stable hybrid formation with oligonucleotides. Consequently, different oligomeric probes can hybridize to the same target with efficiencies that vary by several orders of magnitude. The ability...

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Autors principals: Lahoud, Georges, Timoshchuk, Victor, Lebedev, Alexandre, de Vega, Miguel, Salas, Margarita, Arar, Khalil, Hou, Ya-Ming, Gamper, Howard
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2425472/
https://ncbi.nlm.nih.gov/pubmed/18448471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn209
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