Intracellular Protein Aggregation Is a Proximal Trigger of Cardiomyocyte Autophagy

BACKGROUND: Recent reports demonstrate that multiple forms of cardiovascular stress, including pressure overload, chronic ischemia, and infarction-reperfusion injury, provoke an increase in autophagic activity in cardiomyocytes. However, nothing is known regarding molecular events that stimulate aut...

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Hlavní autoři: Tannous, Paul, Zhu, Hongxin, Nemchenko, Andriy, Berry, Jeff M., Johnstone, Janet L., Shelton, John M., Miller, Francis J., Rothermel, Beverly A., Hill, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601596/
https://ncbi.nlm.nih.gov/pubmed/18541737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.763870
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