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Recruitment of Saccharomyces cerevisiae Dnl4–Lif1 Complex to a Double-Strand Break Requires Interactions With Yku80 and the Xrs2 FHA Domain

Nonhomologous end joining (NHEJ) in yeast depends on eight different proteins in at least three different functional complexes: Yku70–Yku80 (Ku), Dnl4–Lif1–Nej1 (DNA ligase IV), and Mre11–Rad50–Xrs2 (MRX). Interactions between these complexes at DNA double-strand breaks (DSBs) are poorly understood...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Palmbos, Phillip L., Wu, Dongliang, Daley, James M., Wilson, Thomas E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600923/
https://ncbi.nlm.nih.gov/pubmed/18832348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.095539
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