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Recruitment and Dissociation of Nonhomologous End Joining Proteins at a DNA Double-Strand Break in Saccharomyces cerevisiae

Nonhomologous end joining (NHEJ) is an important DNA double-strand-break (DSB) repair pathway that requires three protein complexes in Saccharomyces cerevisiae: the Ku heterodimer (Yku70-Yku80), MRX (Mre11-Rad50-Xrs2), and DNA ligase IV (Dnl4-Lif1), as well as the ligase-associated protein Nej1. Her...

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Detalhes bibliográficos
Main Authors: Wu, Dongliang, Topper, Leana M., Wilson, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278085/
https://ncbi.nlm.nih.gov/pubmed/18245831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.083535
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