Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model

The disseminated characteristics of human glioblastoma multiforme (GBM) make it a particularly difficult tumor to treat with long-term efficacy. Most preclinical models of GBM involve treatment of a single tumor mass. For therapeutic outcomes to translate from the preclinical to the clinical setting...

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Bibliographic Details
Main Authors: King, Gwendalyn D., Muhammad, A.K.M. Ghulam, Curtin, James F., Barcia, Carlos, Puntel, Mariana, Liu, Chunyan, Honig, Sarah B., Candolfi, Marianela, Mondkar, Sonali, Lowenstein, Pedro R., Castro, Maria G.
Format: Artigo
Language:Inglês
Published: Duke University Press 2008
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600834/
https://ncbi.nlm.nih.gov/pubmed/18079358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2007-045
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