Combined Flt3L/TK Gene Therapy Induces Immunological Surveillance Which Mediates an Immune Response Against a Surrogate Brain Tumor Neoantigen

Glioblastoma multiforme (GBM) is a primary brain tumor with a median survival of 14.6 months postdiagnosis. The infiltrative nature of GBM prevents complete resection and residual brain tumor cells give rise to recurrent GBM, a hallmark of this disease. Recurrent GBMs are known to harbor numerous mu...

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Bibliographic Details
Main Authors: King, Gwendalyn D, Muhammad, AKM Ghulam, Larocque, Daniel, Kelson, Kyle R, Xiong, Weidong, Liu, Chunyan, Sanderson, Nicholas SR, Kroeger, Kurt M, Castro, Maria G, Lowenstein, Pedro R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188756/
https://ncbi.nlm.nih.gov/pubmed/21505426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.77
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