Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression

PURPOSE: Glioblastoma multiforme is a deadly primary brain cancer. Because the tumor kills due to recurrences, we tested the hypothesis that a new treatment would lead to immunological memory in a rat model of recurrent glioblastoma multiforme. EXPERIMENTAL DESIGN: We developed a combined treatment...

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Main Authors: Muhammad, A.K.M. Ghulam, Candolfi, Marianela, King, Gwendalyn D., Yagiz, Kader, Foulad, David, Mineharu, Yohei, Kroeger, Kurt M., Treuer, Katherine A., Nichols, W. Stephen, Sanderson, Nicholas S., Yang, Jieping, Khayznikov, Maksim, Van Rooijen, Nico, Lowenstein, Pedro R., Castro, Maria G.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796687/
https://ncbi.nlm.nih.gov/pubmed/19789315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1087
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