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Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

The activity of the homeobox gene Prox1 is necessary and sufficient for venous blood endothelial cells (BECs) to acquire a lymphatic endothelial cell (LEC) fate. We determined that the differentiated LEC phenotype is a plastic, reprogrammable condition that depends on constant Prox1 activity for its...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Johnson, Nicole C., Dillard, Miriam E., Baluk, Peter, McDonald, Donald M., Harvey, Natasha L., Frase, Sharon L., Oliver, Guillermo
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600759/
https://ncbi.nlm.nih.gov/pubmed/19056883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1727208
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