The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells

The homeobox gene Prox1 is crucial for mammalian lymphatic vascular development. In the absence of Prox1, lymphatic endothelial cells (LECs) are not specified. The maintenance of LEC identity also requires the constant expression of Prox1. However, the mechanisms controlling the expression of this g...

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Main Authors: Srinivasan, R. Sathish, Geng, Xin, Yang, Ying, Wang, Yingdi, Mukatira, Suraj, Studer, Michèle, Porto, Marianna P.R., Lagutin, Oleg, Oliver, Guillermo
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849126/
https://ncbi.nlm.nih.gov/pubmed/20360386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1859310
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