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Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3

The phosphoinositide phosphatidylinositol 4-phosphate (PtdIns4P) is an essential signaling lipid that regulates secretion and polarization of the actin cytoskeleton. In Saccharomyces cerevisiae, the PtdIns 4-kinase Stt4 catalyzes the synthesis of PtdIns4P at the plasma membrane (PM). In this paper,...

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Bibliographic Details
Main Authors: Baird, Dan, Stefan, Chris, Audhya, Anjon, Weys, Sabine, Emr, Scott D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600738/
https://ncbi.nlm.nih.gov/pubmed/19075114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804003
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