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The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)P(2) synthesis

Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2), is an essential signalling lipid that regulates key processes such as endocytosis, exocytosis, actin cytoskeletal organization and calcium signalling. Maintaining proper levels of PtdIns(4,5)P(2) at the plasma membrane (PM) is crucial for cell...

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Detalhes bibliográficos
Main Authors: Ling, Yading, Stefan, Christopher J, MacGurn, Jason A, Audhya, Anjon, Emr, Scott D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395088/
https://ncbi.nlm.nih.gov/pubmed/22562153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.127
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