Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells

PEP005 is a novel ingenol angelate that modulates protein kinases C (PKC) functions by activating PKCδ and inhibiting PKCα. This study assessed the antiproliferative effects of PEP005 alone and in combination with several other anticancer agents in a panel of 10 human cancer cell lines characterised...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Benhadji, K A, Serova, M, Ghoul, A, Cvitkovic, E, Le Tourneau, C, Ogbourne, S M, Lokiec, F, Calvo, F, Hammel, P, Faivre, S, Raymond, E
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2008
Предметы:
Translational Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600681/
https://ncbi.nlm.nih.gov/pubmed/19034280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604642
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы