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Solvent dramatically affects protein structure refinement

One of the most challenging problems in protein structure prediction is improvement of homology models (structures within 1–3 Å C(α) rmsd of the native structure), also known as the protein structure refinement problem. It has been shown that improvement could be achieved using in vacuo energy minim...

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Detalhes bibliográficos
Main Authors: Chopra, Gaurav, Summa, Christopher M., Levitt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600579/
https://ncbi.nlm.nih.gov/pubmed/19073921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810818105
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