P2Y(6) receptor-Gα(12/13) signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

Cardiac fibrosis, characterized by excessive deposition of extracellular matrix proteins, is one of the causes of heart failure, and it contributes to the impairment of cardiac function. Fibrosis of various tissues, including the heart, is believed to be regulated by the signalling pathway of angiot...

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Autori principali: Nishida, Motohiro, Sato, Yoji, Uemura, Aya, Narita, Yusuke, Tozaki-Saitoh, Hidetoshi, Nakaya, Michio, Ide, Tomomi, Suzuki, Kazuhiro, Inoue, Kazuhide, Nagao, Taku, Kurose, Hitoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599880/
https://ncbi.nlm.nih.gov/pubmed/19008857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.237
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