Cell Death after Spinal Cord Injury Is Exacerbated by Rapid TNFα-Induced Trafficking of GluR2-Lacking AMPARs to the Plasma Membrane

Glutamate, the major excitatory neurotransmitter in the CNS, is implicated in both normal neurotransmission and excitotoxicity. Numerous in vitro findings indicate that the ionotropic glutamate receptor, AMPAR, can rapidly traffic from intracellular stores to the plasma membrane, altering neuronal e...

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Main Authors: Ferguson, Adam R., Christensen, Randolph N., Gensel, John C., Miller, Brandon A., Sun, Fang, Beattie, Eric C., Bresnahan, Jacqueline C., Beattie, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598739/
https://ncbi.nlm.nih.gov/pubmed/18971481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3708-08.2008
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