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MicroRNA regulation of a cancer network: Consequences of the feedback loops involving miR-17-92, E2F, and Myc

The transcription factors E2F and Myc participate in the control of cell proliferation and apoptosis, and can act as oncogenes or tumor suppressors depending on their levels of expression. Positive feedback loops in the regulation of these factors are predicted—and recently shown experimentally—to l...

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Detalhes bibliográficos
Main Authors: Aguda, Baltazar D., Kim, Yangjin, Piper-Hunter, Melissa G., Friedman, Avner, Marsh, Clay B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598727/
https://ncbi.nlm.nih.gov/pubmed/19066217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811166106
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