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Qualitative Network Modeling of the Myc-p53 Control System of Cell Proliferation and Differentiation
A kinetic model of a molecular control system for the cellular decision to proliferate or differentiate is formulated and analyzed for the purpose of understanding how the system can break down in cancer cells. The proposed core of this control system is composed of the transcription factors Myc and...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207173/ https://ncbi.nlm.nih.gov/pubmed/22067145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.052 |
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