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Practical syntheses of 4-fluoroprolines
4-Fluoroprolines are among the most useful nonnatural amino acids in chemical biology. Here, practical routes are reported for the synthesis of the 2S,4R, 2S,4S, and 2R,4S diastereomers of 4-fluoroproline. Each route starts with (2S,4R)-4-hydroxyproline, which is a prevalent component of collagen an...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2598397/ https://ncbi.nlm.nih.gov/pubmed/19727323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2008.06.024 |
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