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Synthetic Biology of Proteins: Tuning GFPs Folding and Stability with Fluoroproline
BACKGROUND: Proline residues affect protein folding and stability via cis/trans isomerization of peptide bonds and by the C(γ)-exo or -endo puckering of their pyrrolidine rings. Peptide bond conformation as well as puckering propensity can be manipulated by proper choice of ring substituents, e.g. C...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2243022/ https://ncbi.nlm.nih.gov/pubmed/18301757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001680 |
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