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FRA18C: a new aphidicolin‐inducible fragile site on chromosome 18q22, possibly associated with in vivo chromosome breakage

Fragile sites are specific genomic loci that form gaps, constrictions and breaks on chromosomes exposed to replication stress conditions. In the father of a patient with Beckwith‐Wiedemann syndrome and a pure truncation of 18q22‐qter, a new aphidicolin‐sensitive fragile site on chromosome 18q22.2 (F...

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Detalhes bibliográficos
Main Authors: Debacker, Kim, Winnepenninckx, Birgitta, Ben‐Porat, Neta, FitzPatrick, David, Van Luijk, Rob, Scheers, Stefaan, Kerem, Batsheva, Kooy, R Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597991/
https://ncbi.nlm.nih.gov/pubmed/17475918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.044628
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