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The Fragile Breakage versus Random Breakage Models of Chromosome Evolution

For many years, studies of chromosome evolution were dominated by the random breakage theory, which implies that there are no rearrangement hot spots in the human genome. In 2003, Pevzner and Tesler argued against the random breakage model and proposed an alternative “fragile breakage” model of chro...

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Autori principali: Peng, Qian, Pevzner, Pavel A, Tesler, Glenn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378107/
https://ncbi.nlm.nih.gov/pubmed/16501665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020014
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