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The Fragile Breakage versus Random Breakage Models of Chromosome Evolution

For many years, studies of chromosome evolution were dominated by the random breakage theory, which implies that there are no rearrangement hot spots in the human genome. In 2003, Pevzner and Tesler argued against the random breakage model and proposed an alternative “fragile breakage” model of chro...

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Detalhes bibliográficos
Main Authors: Peng, Qian, Pevzner, Pavel A, Tesler, Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378107/
https://ncbi.nlm.nih.gov/pubmed/16501665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020014
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