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Exon skipping through the creation of a putative exonic splicing silencer as a consequence of the cystic fibrosis mutation R553X

Nonsense mutations that occur more than 50 bases upstream of terminal spliced junctions are generally thought to lead to degradation of the corresponding transcripts by the process of nonsense‐mediated mRNA decay. It has also been proposed that some nonsense mutations may affect splicing by the proc...

詳細記述

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書誌詳細
主要な著者: Aznarez, Isabel, Zielenski, Julian, Rommens, Johanna M, Blencowe, Benjamin J, Tsui, Lap‐Chee
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Group 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597982/
https://ncbi.nlm.nih.gov/pubmed/17475917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.045880
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