A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes.

The live vaccine strain (LVS) of Francisella tularensis is killed by human polymorphonuclear leukocytes as a result of strictly oxygen-dependent mechanisms (S. Löfgren, A. Tärnvik, M. Thore, and J. Carlsson, Infect. Immun. 43:730-734, 1984). We now report that a capsule-deficient (Cap-) mutant of LV...

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Autori principali: Sandström, G, Löfgren, S, Tärnvik, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC259783/
https://ncbi.nlm.nih.gov/pubmed/3356465
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