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A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes.

The live vaccine strain (LVS) of Francisella tularensis is killed by human polymorphonuclear leukocytes as a result of strictly oxygen-dependent mechanisms (S. Löfgren, A. Tärnvik, M. Thore, and J. Carlsson, Infect. Immun. 43:730-734, 1984). We now report that a capsule-deficient (Cap-) mutant of LV...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Sandström, G, Löfgren, S, Tärnvik, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1988
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3356465/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.5.1194-1202.1988
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