A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes.

The live vaccine strain (LVS) of Francisella tularensis is killed by human polymorphonuclear leukocytes as a result of strictly oxygen-dependent mechanisms (S. Löfgren, A. Tärnvik, M. Thore, and J. Carlsson, Infect. Immun. 43:730-734, 1984). We now report that a capsule-deficient (Cap-) mutant of LV...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Sandström, G, Löfgren, S, Tärnvik, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3356465/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.5.1194-1202.1988
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