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Testing linkage disequilibrium from pooled DNA: a contingency table perspective
Pooling DNA samples of multiple individuals has been advocated as a method to reduce genotyping costs. Under such a scheme, only the allele counts at each locus, not the haplotype information, are observed. We develop a systematic way for handling such data by formulating the problem in terms of con...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597697/ https://ncbi.nlm.nih.gov/pubmed/18712782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3407 |
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