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Testing linkage disequilibrium from pooled DNA: a contingency table perspective

Pooling DNA samples of multiple individuals has been advocated as a method to reduce genotyping costs. Under such a scheme, only the allele counts at each locus, not the haplotype information, are observed. We develop a systematic way for handling such data by formulating the problem in terms of con...

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Detalhes bibliográficos
Main Authors: Xu, Jinfeng, Yang, Yaning, Ying, Zhiliang, Ott, Jurg
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597697/
https://ncbi.nlm.nih.gov/pubmed/18712782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3407
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