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Mac-1 promotes FcγRIIA-dependent cell spreading and migration on immune complexes
The integrin Mac-1 plays a critical role in Fc receptor (FcR)-mediated antibody-dependent cellular cytotoxicity (ADCC). However, the mechanism by which Mac-1 facilitates the functions of FcγRIIA, a major FcR expressed on human leukocytes, is not fully understood. We report here that Mac-1 sustains c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597675/ https://ncbi.nlm.nih.gov/pubmed/16846215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060529u |
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