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The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers
Ca(2+) release-activated Ca(2+) (CRAC) channels underlie sustained Ca(2+) signaling in lymphocytes and numerous other cells following Ca(2+) liberation from the endoplasmic reticulum (ER). RNAi screening approaches identified two proteins, Stim1, 2 and Orai3-5, that together form the molecular basis...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597643/ https://ncbi.nlm.nih.gov/pubmed/18820677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07338 |
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