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Synthesis of (-)-Δ(9)-trans-Tetrahydrocannabinol - Stereocontrol via Mo-catalyzed Asymmetric Allylic Alkylation Reaction

[Image: see text] Δ(9)-THC is synthesized in enantiomericaly pure form, where all of the stereochemistry is derived from the molybdenum catalyzed asymmetric alkylation reaction of the extremely sterically congested bis-ortho substituted cinnamyl carbonate in high regio- and enantioselectivity.

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Trost, Barry M., Dogra, Kalindi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597621/
https://ncbi.nlm.nih.gov/pubmed/17266321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol063022k
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