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The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP

Individual variations in structure and morphology of amyloid fibrils produced from a single polypeptide are likely to underlie the molecular origin of prion strains and control the efficiency of the species barrier in transmission of prions. Previously, we observed that the shape of amyloid fibrils...

詳細記述

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書誌詳細
主要な著者: Ostapchenko, Valeriy G., Makarava, Natallia, Savtchenko, Regina, Baskakov, Ilia V.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597535/
https://ncbi.nlm.nih.gov/pubmed/18789949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.08.073
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