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Engineering the Quadruplex Fold: Nucleoside Conformation Determines Both Folding Topology and Molecularity in Guanine Quadruplexes

Nucleic acid quadruplexes, based on the guanine quartet, can arise from one or several strands, depending on the sequence. Those consisting of a single strand are folded in one of two principal topologies: antiparallel, in which all or half the guanine stretches are antiparallel to each other, or pa...

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Detalhes bibliográficos
Main Authors: Tang, Chung-Fei, Shafer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597528/
https://ncbi.nlm.nih.gov/pubmed/16637665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0603958
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