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Interplay of guanine oxidation and G-quadruplex folding in gene promoters

Living in an oxygen atmosphere demands an ability to thrive in the presence of reactive oxygen species (ROS). Aerobic organisms have successfully found solutions to the oxidative threats imposed by ROS by evolving an elaborate detoxification system, upregulating ROS during inflammation, and utilizin...

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Pubblicato in:J Am Chem Soc
Autori principali: Fleming, Aaron M., Burrows, Cynthia J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988379/
https://ncbi.nlm.nih.gov/pubmed/31880930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b11050
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