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Design of Amphiphilic Protein Maquettes: Enhancing Maquette Functionality through Binding of Extremely Hydrophobic Cofactors to Lipophilic Domains

We demonstrate coordination of the extremely hydrophobic 13(2)-OH-Ni-bacteriochlorophyll (Ni-BChl) to the lipophilic domain of a novel, designed amphiphilic protein maquette (AP3) dispersed in detergent micelles (accompanying manuscript; Discher et al). Sedimentation velocity and equilibrium experim...

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Detalhes bibliográficos
Main Authors: Noy, Dror, Discher, Bohdana M., Rubtsov, Igor, Hochstrasser, Robin M., Dutton, P. Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597482/
https://ncbi.nlm.nih.gov/pubmed/16156647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050696e
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