ACTIVATION OF INKT CELLS AMELIORATES EXPERIMENTAL OCULAR AUTOIMMUNITY BY A MECHANISM INVOLVING INNATE IFN-γ PRODUCTION AND DAMPENING OF THE ADAPTIVE TH1 AND TH17 RESPONSES

Invariant Natural Killer T cells (iNKT cells) have been reported to play a role not only in innate immunity but also to regulate several models of autoimmunity. Furthermore, iNKT cells are necessary for the generation of the prototypic eye-related immune regulatory phenomenon, anterior chamber assoc...

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Main Authors: Grajewski, Rafael S., Hansen, Anna M, Agarwal, Rajeev K., Kronenberg, Mitchell, Sidobre, Stephane, Su, Shao Bo, Silver, Phyllis B., Tsuji, Moriya, Franck, Richard W., Lawton, Anne P., Chan, Chi-Chao, Caspi, Rachel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597425/
https://ncbi.nlm.nih.gov/pubmed/18802082
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