HITS-CLIP yields genome-wide insights into brain alternative RNA processing

Protein-RNA interactions play critical roles in all aspects of gene expression. Here we develop a genome-wide means of mapping protein-RNA binding sites in vivo, by high throughput sequencing of RNA isolated by crosslinking immunoprecipitation (HITS-CLIP). HITS-CLIP analysis of the neuron-specific s...

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Detaylı Bibliyografya
Asıl Yazarlar: Licatalosi, Donny D., Mele, Aldo, Fak, John J., Ule, Jernej, Kayikci, Melis, Chi, Sung Wook, Clark, Tyson A., Schweitzer, Anthony C., Blume, John E., Wang, Xuning, Darnell, Jennifer C., Darnell, Robert B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597294/
https://ncbi.nlm.nih.gov/pubmed/18978773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07488
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