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Probing the Role of a Secondary Structure Element at the 5′- and 3′-Splice Sites in Group I Intron Self-splicing: The Tetrahymena L-16 ScaI Ribozyme Reveals a New Role of the G•U Pair in Self-splicing
Several ribozyme constructs have been used to dissect aspects of the group I self-splicing reaction. The Tetrahymena L-21 ScaI ribozyme, the best studied of these intron analogs, catalyzes a reaction analogous to the first step of self-splicing, in which a 5′-splice site analog (S) and guanosine (G)...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597287/ https://ncbi.nlm.nih.gov/pubmed/17385892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062169g |
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