Llwytho...

The decoupling of Smoothened from Gα(i) proteins has little effect on Gli3 protein processing and Hedgehog-regulated chick neural tube patterning

The Hedgehog (Hh) signal is transmitted by two receptor molecules, Patched (Ptc) and Smoothened (Smo). Ptc suppresses Smo activity, while Hh binds Ptc and alleviates the suppression, which results in activation of Hh targets. Smo is a seven-transmembrane protein with a long carboxyl terminal tail. V...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Low, Wee-Chuang, Wang, Chengbing, Pan, Yong, Huang, Xin-Yun, Chen, James K., Wang, Baolin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597282/
https://ncbi.nlm.nih.gov/pubmed/18590719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.06.014
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