cGMP-independent anti-tumour actions of the inhibitor of soluble guanylyl cyclase, ODQ, in prostate cancer cell lines

BACKGROUND AND PURPOSE: Soluble guanylyl cyclase (sGC) is a receptor for nitric oxide that generates cGMP. This second messenger molecule has established roles in cellular physiology; however, less is known about its effects in tumour cells. EXPERIMENTAL APPROACH: The effects of 1H-[1,2,4]oxadiazolo...

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Detalles Bibliográficos
Autores principales: Haramis, G, Zhou, Z, Pyriochou, A, Koutsilieris, M, Roussos, C, Papapetropoulos, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597233/
https://ncbi.nlm.nih.gov/pubmed/18695639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.312
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