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cGMP-independent anti-tumour actions of the inhibitor of soluble guanylyl cyclase, ODQ, in prostate cancer cell lines
BACKGROUND AND PURPOSE: Soluble guanylyl cyclase (sGC) is a receptor for nitric oxide that generates cGMP. This second messenger molecule has established roles in cellular physiology; however, less is known about its effects in tumour cells. EXPERIMENTAL APPROACH: The effects of 1H-[1,2,4]oxadiazolo...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597233/ https://ncbi.nlm.nih.gov/pubmed/18695639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.312 |
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