Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPα

Hepcidin is the principal iron regulatory hormone, controlling the systemic absorption and remobilization of iron from intracellular stores. Recent in vivo studies have shown that hepcidin is down-regulated by erythropoiesis, anemia, and hypoxia, which meets the need of iron input for erythrocyte pr...

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Detalhes bibliográficos
Main Authors: Pinto, Jorge P., Ribeiro, Sara, Pontes, Helena, Thowfeequ, Shifaan, Tosh, David, Carvalho, Félix, Porto, Graça
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
RED CELLS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597200/
https://ncbi.nlm.nih.gov/pubmed/18326822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-106195
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