Therapeutic efficacy of (177)Lu-CHX-A″-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy

BACKGROUND: This study investigated the biodistribution and therapeutic efficacy of Lutetium-177 ((177)Lu) radiolabeled anti-Lewis Y monoclonal antibody hu3S193 radioimmunotherapy (RIT) in mice bearing prostate cancer xenografts. The ability of Epidermal Growth Factor Receptor (EGFR) tyrosine kinase...

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Detalhes bibliográficos
Main Authors: Kelly, Marcus P, Lee, Sze Ting, Lee, F-T, Smyth, Fiona E, Davis, Ian D., Brechbiel, Martin W, Scott, Andrew M
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597150/
https://ncbi.nlm.nih.gov/pubmed/18942092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20856
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