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Graft rejection as a Th1-type process amenable to regulation by donor Th2-type cells through an interleukin-4/STAT6 pathway

Graft rejection has been defined as the mirror image of graft-versus-host disease, which is biologically characterized primarily as a Th1-type process. As such, we reasoned that graft rejection would represent a Th1 response amenable to Th2 modulation. Indeed, adoptive transfer of host Th1-type cell...

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Autors principals: Mariotti, Jacopo, Foley, Jason, Ryan, Kaitlyn, Buxhoeveden, Nicole, Kapoor, Veena, Amarnath, Shoba, Fowler, Daniel H.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597142/
https://ncbi.nlm.nih.gov/pubmed/18625883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-154278
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