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Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors

An effective response to extreme hematopoietic stress requires an extreme elevation in hematopoiesis and preservation of hematopoietic stem cells (HSCs). These diametrically opposed processes are likely to be regulated by genes that mediate cellular adaptation to physiologic stress. Herein, we show...

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Autori principali: Cao, Yu-An, Wagers, Amy J., Karsunky, Holger, Zhao, Hui, Reeves, Robert, Wong, Ronald J., Stevenson, David K., Weissman, Irving L., Contag, Christopher H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597124/
https://ncbi.nlm.nih.gov/pubmed/18509090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-127621
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