Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation

Sirolimus is an effective agent used in graft-versus-host disease (GVHD) prophylaxis after allogeneic transplantation. It also has antiproliferative effects on vascular endothelium when used to coat coronary artery stents. We noted an excess of veno-occlusive disease (VOD) in a clinical trial, and r...

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Auteurs principaux: Cutler, Corey, Stevenson, Kristen, Kim, Haesook T., Richardson, Paul, Ho, Vincent T., Linden, Erica, Revta, Carolyn, Ebert, Ruth, Warren, Diane, Choi, Sung, Koreth, John, Armand, Philippe, Alyea, Edwin, Carter, Shelly, Horowitz, Mary, Antin, Joseph H., Soiffer, Robert
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2008
Sujets:
Clinical Trials and Observations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597119/
https://ncbi.nlm.nih.gov/pubmed/18776081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-169342
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