Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation

Sirolimus is an effective agent used in graft-versus-host disease (GVHD) prophylaxis after allogeneic transplantation. It also has antiproliferative effects on vascular endothelium when used to coat coronary artery stents. We noted an excess of veno-occlusive disease (VOD) in a clinical trial, and r...

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Detalhes bibliográficos
Main Authors: Cutler, Corey, Stevenson, Kristen, Kim, Haesook T., Richardson, Paul, Ho, Vincent T., Linden, Erica, Revta, Carolyn, Ebert, Ruth, Warren, Diane, Choi, Sung, Koreth, John, Armand, Philippe, Alyea, Edwin, Carter, Shelly, Horowitz, Mary, Antin, Joseph H., Soiffer, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597119/
https://ncbi.nlm.nih.gov/pubmed/18776081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-169342
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