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Toxoid of Pseudomonas aeruginosa exotoxin A generated by deletion of an active-site residue.
Glutamic acid-553 of Pseudomonas aeruginosa exotoxin A (ETA), identified previously as an active-site residue, was deleted by oligonucleotide-directed mutagenesis of the cloned toxin gene in Escherichia coli. The purified mutant toxin was stable, fully immunoreactive, and capable of blocking toxin r...
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| Publicado no: | Infect Immun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259707/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2460407/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.12.3095-3098.1988 |
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