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Toxoid of Pseudomonas aeruginosa exotoxin A generated by deletion of an active-site residue.

Glutamic acid-553 of Pseudomonas aeruginosa exotoxin A (ETA), identified previously as an active-site residue, was deleted by oligonucleotide-directed mutagenesis of the cloned toxin gene in Escherichia coli. The purified mutant toxin was stable, fully immunoreactive, and capable of blocking toxin r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lukac, M, Pier, G B, Collier, R J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1988
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC259707/
https://ncbi.nlm.nih.gov/pubmed/2460407
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