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Pseudomonas exotoxin A: toxoid preparation by photoaffinity inactivation.

A method for toxoid preparation has been developed in which toxins expressing enzymatic activity can be detoxified by photoaffinity labeling techniques. In the case of Pseudomonas aeruginosa exotoxin A, the method relies on the affinity of azido-substituted analogs of the substrate (NAD) for the pro...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Marburg, S, Tolman, R L, Callahan, L T
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6407002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.10.2870
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