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PPAR Ligand MCC-555 Suppresses Intestinal Polyps in APC(Min+) Mice via ERK and PPAR Dependent Pathways
A large body of studies has suggested that peroxisome proliferator-activated receptor γ (PPARγ) ligands, such as thiazolidinedione, are potent candidates for chemopreventive agents. MCC-555 is a PPARγ/α dual agonist and has been previously shown to induce apoptosis in vitro; however, the molecular m...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597004/ https://ncbi.nlm.nih.gov/pubmed/18790758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0173 |
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