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αConotoxin ArIB[V11L,V16D] is a potent and selective antagonist at rat and human native α7 nicotinic acetylcholine receptors

A recently developed α-conotoxin, α-CtxArIB[V11L,V16D] is a potent and selective competitive antagonist at rat recombinant α7 nicotinic acetylcholine receptors (nAChRs), making it an attractive probe for this receptor subtype. α7 nAChRs are potential therapeutic targets that are widely expressed in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Innocent, Neal, Livingstone, Phil D., Hone, Arik, Kimura, Atsuko, Young, Tracey, Whiteaker, Paul, McIntosh, J. Michael, Wonnacott, Susan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596936/
https://ncbi.nlm.nih.gov/pubmed/18664588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.142943
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